- Goljan Video Lectures
- Goljan Notes Pdf
- Goljan Audio Torrent
- Dr Goljan Audio Lectures
- Goljan Pathology Lectures
- Goljan Pathology Audio Lectures Download
- Goljan Lecture Notes
Goljan Pathology Lecture Notes PDF Free Download Section. Now, in this section of the article, you will be able to get access to the Goljan Pathology Lecture Notes PDF Free Download file in.pdf format. The Goljan Pathology Lecture Notes PDF Free Download file has been uploaded to an online repository for the safer downloading. File Size: 1.26 MB.
Download Goljan USMLE Step 1 Audio Lectures Free
Today we will share stuff related to Medical Audios. We will share Goljan Pathology Audio Lectures (Complete Lectures). Links to Download Audio Lectures are given bellow.
Content sample from Audio Lectures:
“1. Most imp: have to go into anaerobic glycolysis; end product is lactic acid (pyruvate is converted to lactate b/c of increased NADH); need to make NAD, so that the NAD can feedback into the glycolytic cycle to make 2 more ATP. Why do we have to use anaerobic glycolysis with tissue hypoxia? Mitochondria are the one that makes ATP; however, with anaerobic glycolysis, you make 2 ATP without going into the mitochondria. Every cell (including RBC’s) in the body is capable of
performing anaerobic glycolysis, therefore surviving on 2 ATP per glucose if you have tissue hypoxia. Mitochondrial system is totally shut down (no O2 at the end of the electron transport system – can only get 2 ATP with anaerobic glycolysis). Good news – get 2 ATP Bad news – build up of lactic acid in the cell and outside the cell (increased anion-gap metabolic acidosis with tissue hypoxia) due to lactic acidosis from anaerobic glycolysis. However, causes havoc inside the cell b/c increase of acid within a cell will denature proteins (with structural proteins messed up, the configuration will be altered); enzymes will be denatured, too. As a result, cells cannot autodigest anymore b/c enzymes are destroyed b/c buildup of acid. Tissue hypoxia will therefore lead to COAGULATION necrosis (aka infarction). Therefore, buildup of lactic acid within the cell will lead to Coagulation necrosis.
2. 2nd problem of lacking ATP: all ATP pumps are screwed up b/c they run on ATP. ATP is the power, used by muscles, the pump, anything that needs energy needs ATP. Na/K pump – blocked by digitalis to allow Na to go into cardiac muscle, so Ca channels open to increase force of contraction (therefore, sometimes you want the pump blocked), and sometimes you want to enhance it.
With no ATP, Na into the cell and it brings H20, which leads to cellular swelling (which is reversible). Therefore, with tissue hypoxia there will be swelling of the cell due to decreased ATP (therefore will get O2 back, and will pump it out – therefore it is REVERSABLE).
In true RBC, anaerobic glycolysis is the main energy source b/c they do not have mitochondria; not normal in other tissues (want to utilize FA’s, TCA, etc)”
With no ATP, Na into the cell and it brings H20, which leads to cellular swelling (which is reversible). Therefore, with tissue hypoxia there will be swelling of the cell due to decreased ATP (therefore will get O2 back, and will pump it out – therefore it is REVERSABLE).
In true RBC, anaerobic glycolysis is the main energy source b/c they do not have mitochondria; not normal in other tissues (want to utilize FA’s, TCA, etc)”
- Now in this section of the article, you will be able to get access to the Goljan Rapid Review Pathology 5th Edition PDF Free Download file in.pdf format. Goljan Rapid Review Pathology 5th Edition PDF Free Download file has been uploaded to an online repository for the safe downloading. File Size: 422 MB.
- Sep 10, 2017 37 videos Play all Goljan Lectures - Step 1 Elisha Maria Study LESS Study SMART - Motivational Video on How to Study EFFECTIVELY - Duration: 12:04. Motivation2Study 2,483,290 views.
You may also be interested in:
Download Goljan USMLE Step 1 Audio Lectures Free
Alright, now in this part of the article, you will be able to access the free Goljan USMLE Step 1 Audio Lectures using our direct links mentioned at the end of this article. We have uploaded a genuine Goljan USMLE Step 1 Audio Lectures to our online file repository so that you can enjoy a blazing-fast and safe downloading experience.
Here’s the cover image preview of Goljan USMLE Step 1 Audio Lectures:
Kkmoon endoscope drivers for pc, KKmoon 8mm 2m Mini Digital USB Endoscope Inspection Camera Adjustable Brightness for PC. KKmoon 7 Inch Video Door Phone Doorbell Intercom Kit 1-camera 2-monitor Night Vision. KKmoon ACR RFID Reader and Writer Access contorl with USB SDK and 5pcs IC Card. KKmoon Door Lock Access Control System, kkmoom pc rar software, kkmoom pc rar download. Usb 2.0 pc camera software free download How to uninstall software update on android phone How to update android software Google is an online store that delivers software for android devices. Kkmoon software Endoscope software Endoscope camera software Usb endoscope software android Dbpower endoscope software Usb endoscope camera software Depstech endoscope software Usb. TOMTOP use cookies to give you the best shopping experience. If you continue to use our services or create a new account, we will assume that you agree to our. 44 rows Download KKMOON for PC - free download KKMOON for PC/Mac/Windows 7,8,10, Nokia. Kkmoon pc download. KKMOON is a kind of network camera viewing software Has the following features: 1. View the real-time video 2. Take photo for real-time video 3. Ptz control 4. Video playback in the SD Card 5. Time zone Settings and mobile phone time Synchronization.
Please use the direct link mentioned below to download Goljan USMLE Step 1 Audio Lectures free now:
Goljan Rapid Review Pathology |
Download |
Goljan Rapid Review 4th Edition |
Download |
Goljan Audio (5 days) |
Day 1 |
Goljan-High-Yield (Step 1 Remembered Questions) |
Download |
Goljan Pathology Audio Transcripts |
Download |
Goljan Pictures With Notes |
Download |
Goljan Slides |
Download |
Goljan Qbanks |
Goljan Patho Qbank-Immunology.zip |
Goljan Patho Qbank-Histology.zip |
Goljan Patho Qbank-Biostatistics.zip |
Goljan Patho Qbank-Pathology.zip |
Goljan Patho Qbank-Microbiology.zip |
Goljan Step 1 High Yields.apkg (Anki) |
Goljan_High_yield_Pathology_Questions.pdf |
Kindly support us by sharing this Post with your friends.
Disclaimer:
This site complies with DMCA Digital Copyright Laws.Please bear in mind that we do not own copyrights to this book/software. We’re sharing this with our audience ONLY for educational purpose and we highly encourage our visitors to purchase original licensed software/Books. If someone with copyrights wants us to remove this software/Book, please contact us. immediately.
This site complies with DMCA Digital Copyright Laws.Please bear in mind that we do not own copyrights to this book/software. We’re sharing this with our audience ONLY for educational purpose and we highly encourage our visitors to purchase original licensed software/Books. If someone with copyrights wants us to remove this software/Book, please contact us. immediately.
You may send an email to [email protected] or [email protected] for all DMCA / Removal Requests.
In today’s article, we will share the .pdf file for the Goljan Pathology Lecture Notes. We have uploaded the Goljan Pathology Lecture Notes PDF file to our online repository for the safer downloading of the file. Goljan Lecture Notes are considered very high yield for the USMLE Step 1 preparation.
Goljan Video Lectures
Sample Lectures
![Goljan lectures download free Goljan lectures download free](/uploads/1/2/5/0/125051222/163492694.jpg)
- Hypoxia = inadequate oxygenation of tissue (same definition of a shock). Need O2 for oxidation phosphorylation pathway – where you get ATP from inner Mito membrane (electron transport system, called oxidative phosphorylation). The last rxn is O2 to receive the electrons. Protons are being kicked off, go back into the membrane, and form ATP, and ATP informed in the mitochondria
- Terms:
- Oxygen content = Hb x O2 satn + partial pressure of arterial oxygen (these are the 3 main things that carry O2 in our blood)
In Hb, the O2 attaches to heme group (O2 sat’n) Partial pressure of arterial O2 is O2 dissolved in plasma In RBC, four heme groups (Fe must be +2; if Fe+ is +3, it cannot carry O2) Therefore, when all four heme groups have an O2 on it, the O2 sat’n is 100%.
Goljan Notes Pdf
- O2 sat’n is the O2 IN the RBC is attached TO the heme group = (measured by a pulse oximeter)
- Partial pressure of O2 is O2 dissolved in PLASMA
Goljan Audio Torrent
O2 flow: from alveoli through the interphase, then dissolves in plasma, and increases the partial pressure of O2, diffuses through the RBC membrane and attaches to the heme groups on the RBC on the Hb, which is the O2 sat’n
Dr Goljan Audio Lectures
Therefore – if the partial pressure of O2 is decreased, O2 sat’n HAS to be decreased (B/c O2 came from the amount that was dissolved in plasma)
- Causes of tissue hypoxia:
- Ischemia (decrease in ARTERIAL blood flow ……NOT venous)
MCC Ischemia is thrombus in the muscular artery (b/c this is the mcc death in USA = MI, therefore MI is a good example of ischemia b/c thrombus is blocking arterial blood flow, producing tissue hypoxia) Download pokemon crystal free.
Other causes of tissue ischemia: decrease in Cardiac Output (leads to hypovolemia and cardiogenic shock) b/c there is a decrease in arterial blood flow.
- 2 nd MCC of tissue hypoxia = hypoxemia
Hypoxia = ‘big’ term
Hypoxemia = cause of hypoxia (they are not the same); deals with the partial pressure of arterial O2 (O2 dissolved in arterial plasma, therefore, when the particle pressure of O2 is decreased, this is called hypoxemia). Here are 4 causes of hypoxemia:
- Resp acidosis (in terms of hypoxemia) – in terms of Dalton’s law, the sum of the partial pressure of gas must = 760 at atmospheric pressure (have O2, CO2, and nitrogen; nitrogen remains constant – therefore, when you retain CO2, this is resp acidosis; when CO2 goes up, pO2 HAS to go down b/c must have to equal 760; Therefore, every time you have resp acidosis, from ANY cause, you have hypoxemia b/c low arterial pO2; increase CO2= decrease pO2, and vice versa in resp alkalosis).
- Ventilation defects – best example is resp distress syndrome (aka hyaline membrane dz in children). In adults, this is called Adult RDS, and has a ventilation defect. Lost ventilation to the alveoli, but still have perfusion; therefore have created an intrapulmonary shunt. Exam question: pt with hypoxemia, given 100% of O2 for 20 minutes, and pO2 did not increase, therefore indicates a SHUNT, massive ventilation defect.
- Perfusion defects – knock off blood flow
MCC perfusion defect = pulmonary embolus, especially in prolonged flights, with sitting down and not getting up.
Stasis in veins of the deep veins leads to propagation of a clot and 3-5 days later an embolus develops and embolizes.
Goljan Pathology Lectures
In this case, you have ventilation, but no perfusion; therefore there is an increase in dead space. If you give 100% O2 for a perfusion defect, pO2 will go UP (way to distinguish vent from perfusion defect), b/c not every single vessel in the lung is not perfused.
Therefore, perfusion defects because of an increase in dead space, while ventilation defects cause intrapulmonary shunts.
To tell the difference, give 100% O2 and see whether the pO2 stays the same, i.e does not go up (shunt) or increases (increase in dead space).
** Recommended Downloads **
Goljan Pathology Lecture Notes PDF Free Download Section
Now, in this section of the article, you will be able to get access to the Goljan Pathology Lecture Notes PDF Free Download file in .pdf format. The Goljan Pathology Lecture Notes PDF Free Download file has been uploaded to an online repository for the safer downloading.
File Size: 1.26 MB
Goljan Pathology Audio Lectures Download
Happy learning people!
Goljan Lecture Notes
Disclaimer:This site complies with DMCA Digital Copyright Laws. Please bear in mind that we do not own copyrights to these books. We’re sharing this material with our valuable users ONLY for educational purpose and we highly encourage our visitors to purchase original books from the respected publishers. If someone with copyrights wants us to remove this content, please contact us immediately.
Please Send an email at [email protected] for any DMCA/removal.